Lamento: Beyond the Void (2006)

The game takes place in a fictional world inhabited by Ribika (who look like humans but have cat ears and tails). Their world has fallen into dark times -- a mysterious void has made some places (and even animals) impossible to touch, causing major food shortages. A strange and deadly disease that has killed off a large percentage of the female Ribika population is also spreading. The hero, Konoe, exists in this miserable world, living alone in the starving village of Karou who have turned to cannibalism. The story begins with Konoe in Karou, where he suddenly begins to see horrible dreams and strange marks appear on his body. This is believed to be a curse so Konoe heads off to Ransen (the big city) in order to heal his body...